| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268098 | Tetrahedron Letters | 2015 | 4 Pages |
Abstract
The reactions of esters and amides of 3-phenylpropynoic acid with strong Lewis acids AlX3 (X = Cl, Br) or conjugate Brønsted-Lewis superacids HX-AlX3 (X = Cl, Br) in benzene and cyclohexane at room temperature afforded 3,3-diphenylpropanoic acid derivatives in up to 94% yield. This tandem reaction of the acetylene bond proceeded by hydrophenylation followed by ionic hydrogenation.
Graphical abstractDownload high-res image (58KB)Download full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Denis I. Nilov, Aleksander V. Vasilyev,