Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268199 | Tetrahedron Letters | 2015 | 4 Pages |
Abstract
We report a practical high-yield synthesis of 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines using a base-assisted cyclocondensation of chalcone and 1,2,4-triazol-3-amine in an open reaction vessel. The same conditions can also be used for the preparation of novel imidazo[1,2-a]pyrimidine derivatives.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xinhua He, Shaymaa E. Kassab, Geoffrey Heinzl, Fengtian Xue,