| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268210 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
This Letter describes the first report of a highly stereoselective synthesis of triethereal cyclohexanones via copper(I) mediated 1,4-addition of organometallic reagents to glucose-derived triethereal cyclohexenone. The cyclohexanones generated can be reduced with modest stereoselectivity to afford a variety of substituted inositol derivatives as potential pyranose sugar mimetics. The protocol generated a range of substituted cyclohexanones in good yield as single stereoisomers.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jianwei Bian, Steven R. Schneider, Robert J. Maguire,