Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268319 | Tetrahedron Letters | 2015 | 5 Pages |
Abstract
An environmentally friendly synthetic route by the application of CO2 to synthesize amides via in situ protection and deprotection of amines for iron catalyzed oxidative amidation of aldehydes was developed. Various secondary and tertiary amides have been synthesized in moderate to good yields under mild and neutral reaction conditions. The use of amine hydrochloride salts and hence base for neutralization step is totally avoided in this protocol.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thulasiram Bathini, Vikas S. Rawat, Sreedhar Bojja,