Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268360 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
Insertion of allenyl carbenoids (3-tosyloxy-1-lithioalk-1-ynes) into organozirconium complexes gave allenyl-zirconocenes via a 1,2-zirconate rearrangement. Trapping of the allenyl-zirconium species with aldehydes and ketones gave, after hydrolysis, a series of homopropargyl alcohols. Enantioenriched products were prepared by insertion of the lithium carbenoid derived from (S)-but-3-yn-2-yl 4-toluenesulfonate into alkyl- and alkenyl-chlorozirconocenes.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jozef Stec, Alan R. Henderson, Richard J. Whitby,