| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268368 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
The pseudo five-component domino reactions of (E)-3-(dimethylamino)-1-arylprop-2-en-1-one, formaldehyde and aniline afford 5-aroyl-1,3-diarylhexahydropyrimidines in good yields under catalyst-free conditions. This transformation involving 4 C-N and 1 C-C bond formations in a one pot operation presumably proceeds via Michael addition-elimination-Mannich type reaction-condensative annulation-reduction sequence.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sivasubramanian Muthusaravanan, Subbu Perumal, Abdulrahman I. Almansour,