Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268396 | Tetrahedron Letters | 2015 | 4 Pages |
Abstract
We report herein a new and effective method for additive-free trifluoromethylation of aromatic aldehydes with TMSCF3. Normal acidic hydrolysis for desilylation in the workup process is not required in this transformation. This reaction presents a new environmentally friendly protocol to access trifluoromethylated benzyl alcohols.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jing Sun, Xinhua Peng, Hao Guo,