Article ID Journal Published Year Pages File Type
5268396 Tetrahedron Letters 2015 4 Pages PDF
Abstract

We report herein a new and effective method for additive-free trifluoromethylation of aromatic aldehydes with TMSCF3. Normal acidic hydrolysis for desilylation in the workup process is not required in this transformation. This reaction presents a new environmentally friendly protocol to access trifluoromethylated benzyl alcohols.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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