Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268425 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
An efficient non-ionic surfactant catalyzed multicomponent synthesis of novel benzylamino coumarin derivatives has been developed from secondary amines, aromatic aldehyde, and 4-hydroxy coumarin via Mannich type reaction in aqueous media. In this Mannich type reaction, surfactant forms stable colloidal medium to stabilize iminium ion which undergoes nucleophilic addition of 4-hydroxy coumarin to give benzylamino coumarin in very good yields.
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Authors
Atul Kumar, Maneesh Kumar Gupta, Mukesh Kumar,