| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268469 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Several Lewis acids were investigated as promoters in the intermolecular or intramolecular direct N-acylation reaction of sulfonamides using carboxylic ester as an acylating agent. TiCl4 was found to possess the highest activity and enhanced efficiently sulfonamide to form N-acylsulfonamides under optimized conditions. This method provides a novel approach to make N-acylsulfonamides from ester via an easy work-up procedure.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Shaomin Fu, Xiaoyan Lian, Tongmei Ma, Wenhua Chen, Meifang Zheng, Wei Zeng,