| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268496 | Tetrahedron Letters | 2015 | 5 Pages |
Abstract
A transition metal-free, one-pot protocol has been developed for the synthesis of 11H-indolo[3,2-c]isoquinolin-5-amines via the atom economical annulation of ethyl (2-cyano-phenyl)carbamates and 2-cyanobenzyl bromides. This method proceeds via sequential N-alkylation and base-promoted cyclization. Optimization data, substrate scope, mechanistic insights, and photoluminescence properties are discussed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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