Article ID Journal Published Year Pages File Type
5268594 Tetrahedron Letters 2011 5 Pages PDF
Abstract

The mechanism of the three component base mediated Biginelli dihydropyrimidines synthesis was investigated using Accurate Mass TOF LC-MS-ESI and Tandem TOF LC-MS-ESI. We suggest hemiaminal as a possible intermediate leading to the formation of Biginelli product. Under our current experimental conditions we did not observe any bis-ureide as reported by ji et al.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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