Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268608 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
An improved methodology for the synthesis of substituted pyrido[2,3-d]pyrimidinediones from 6-aminouracils and the corresponding enaminone has been developed which provides high yields via an operationally simple process. The method has been extended to encompass a range of electron-rich enaminones, a substrate class that does not perform well under the standard conditions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gwydion H. Churchill, Steven A. Raw, Lyn Powell,