Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268658 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A novel, cheap copper(II) fluoride-mediated N-arylation of heterocycles with halothiophenes is described. The yield of the pyrazolylthiophene strongly depends on the nature of the initial thiophene. The molecular structure of 3,5-dimethyl-1-(5′-methyl-[2,2′]bithienyl-5-yl)-1H-pyrazole was studied by X-ray diffraction.
Graphical abstractCopper(II) fluoride-mediated N-arylation of heterocycles with halothiophenes is described. The yield of the pyrazolylthiophene depends strongly on the nature of the initial thiophene.Figure optionsDownload full-size imageDownload as PowerPoint slide
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