Article ID Journal Published Year Pages File Type
5268658 Tetrahedron Letters 2010 4 Pages PDF
Abstract

A novel, cheap copper(II) fluoride-mediated N-arylation of heterocycles with halothiophenes is described. The yield of the pyrazolylthiophene strongly depends on the nature of the initial thiophene. The molecular structure of 3,5-dimethyl-1-(5′-methyl-[2,2′]bithienyl-5-yl)-1H-pyrazole was studied by X-ray diffraction.

Graphical abstractCopper(II) fluoride-mediated N-arylation of heterocycles with halothiophenes is described. The yield of the pyrazolylthiophene depends strongly on the nature of the initial thiophene.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry