| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268663 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
An expedient synthetic procedure of indolo[1,2-a]quinolines was developed using a sequential Cu-mediated N-arylation of indole, Mn(OAc)3-mediated oxidative free radical cyclization, and NaI/O2-assisted concomitant dealkoxycarbonylation/aerobic oxidation. The last step was replaced by a palladium-catalyzed decarboxylation/elimination protocol for the allyl ester derivatives.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![An expedient synthesis of indolo[1,2-a]quinolines via Mn(OAc)3-mediated oxidative free radical cyclization and NaI/O2-assisted dealkoxycarbonylation/aerobic oxidation cascade](/preview/png/5268663.png "First Page Preview: An expedient synthesis of indolo[1,2-a]quinolines via Mn(OAc)3-mediated oxidative free radical cyclization and NaI/O2-assisted dealkoxycarbonylation/aerobic oxidation cascade")
Authors
Hyun Seung Lee, Se Hee Kim, Yu Mi Kim, Jae Nyoung Kim,