Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268762 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
The rhodium-catalyzed diastereo- and enantioselective Michael addition of arylboronic acids to 3-alkylenyloxindoles has been developed with (R)-binap as a ligand. A wide variety of the desired functionalized oxindoles are smoothly obtained in high yields (up to 99%) with high enantioselectivities (up to 92% ee) and good diastereoselectivities (up to 82:18).
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiangyang Zhang, Guihua Chen, Peng Cao, Jibing Liu, Jian Liao,