Article ID Journal Published Year Pages File Type
5268836 Tetrahedron Letters 2010 4 Pages PDF
Abstract
KF-alumina was found to be an efficient base for the synthesis of sterically hindered α-substituted carboxylic acids. A series of Bargellini reactions were performed by using various substituted anilines, phenols, and thiophenols as nucleophiles with ketones in the presence of chloroform and KF-alumina as a base. All the compounds were fully characterized.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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