Article ID Journal Published Year Pages File Type
5269014 Tetrahedron Letters 2015 4 Pages PDF
Abstract

A facile and efficient base promoted one-pot dimerization of halo cyclohexene derivatives leading to a de novo synthesis of biologically important diarylmethane and diarylmethanone derivatives is reported. A plausible mechanism for the unexpected formation of the title compounds involves dehydrohalogenation, 1,6-conjugate addition, subsequent aromatization through C–C bond cleavage and dehydrohalogenation.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry