Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269104 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
Chiral Nβ-Fmoc amino alkyl isonitriles were employed in Ugi multi component reactions (Ugi 4C-3CR) to obtain functionalized β-lactam peptidomimetics with l-aspartic acid α-methyl ester/peptide ester and organic aldehydes as other components. The reactions were carried out in MeOH. Thirteen Ugi products have been prepared in good to moderate yields with good diastereoselectivities.
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Authors
T.M. Vishwanatha, N. Narendra, Vommina V. Sureshbabu,