Article ID Journal Published Year Pages File Type
5269104 Tetrahedron Letters 2011 5 Pages PDF
Abstract
Chiral Nβ-Fmoc amino alkyl isonitriles were employed in Ugi multi component reactions (Ugi 4C-3CR) to obtain functionalized β-lactam peptidomimetics with l-aspartic acid α-methyl ester/peptide ester and organic aldehydes as other components. The reactions were carried out in MeOH. Thirteen Ugi products have been prepared in good to moderate yields with good diastereoselectivities.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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