Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269140 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
1,4-Disubstituted 1,3-dialkynes were obtained from the one-pot palladium/copper-catalyzed coupling reactions of aryl iodide and propiolic acid. The optimized catalytic system consisted of 5.0 mol % Pd(PPh3)2Cl2, 10 mol % dppb, 10 mol % CuI, 2.4 equiv of DBU, and 1.2 equiv of K2CO3. The coupling reaction was carried out at 30 °C for 6 h and subsequently at 80 °C for 3 h.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yong Kim, Ahbyeol Park, Kyungho Park, Sunwoo Lee,