Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269149 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A method for the chemoselective reduction of Ugi-type lactam amides at the lactam carbonyl functionality with borane complexes has been developed. The novel reduction products can be further manipulated synthetically to yield various novel N- and C-terminally active unnatural amino acid building blocks.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alan Tsaloev, Alexei Ilyin, Sergey Tkachenko, Alexandre Ivachtchenko, Dmitry Kravchenko, Mikhail Krasavin,