Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269256 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
The use of commercially available 2,6-bis(diphenylphosphino)pyridine as a ligand in conjunction with K2CO3, DMAc and TBAB is an effective method for the palladium-catalyzed CN coupling of a variety of aryl halides with anilines, N-heterocyclic aromatic amines, and a cyclic secondary amine. The reactions proceed in good to excellent yield (up to 98%) while the loading of Pd(OAc)2 was as low as 0.025 mol %.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shirin Nadri, Ezzat Rafiee, Sirous Jamali, Mohammad Joshaghani,