| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5269313 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Conditions for bromination at the C3 and C5 positions of a 1,4-dihydropyridine (DHP) were investigated. The effect of base concentration, base type, reaction temperature, and solvent were examined. DHP derivatives with ester and amide moieties were synthesized and brominated. The bromine atoms can be replaced by other substituents, utilizing Suzuki cross coupling.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ori Rorlik, Zeev Tashma, Claudia M. Barzilay, Morris Srebnik,