Article ID Journal Published Year Pages File Type
5269346 Tetrahedron Letters 2011 4 Pages PDF
Abstract

Multi-substituted tetrahydropyrans (THPs) have been prepared via a one-pot, In(OTf)3-catalyzed, sequential allyl-/crotylboration-Prins cyclization. The homoallylic borate intermediate formed during the allyl- and crotylboration was converted in situ to an oxocarbenium ion and trapped with a nucleophile. The reaction has been extended to include a one-pot allylboration–cross Prins cyclization as well.

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Physical Sciences and Engineering Chemistry Organic Chemistry