| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5269359 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Reaction of 11-aminoacronycine, 10-aminobenzo[a]acronycine, and 10-aminobenzo[b]acronycine with paraformaldehyde gave the corresponding Tröger's bases 11, 14, and 16, respectively. The cytotoxic activity of those three new compounds was determined against L-1210 leukemia and KB-3-1 solid tumor cell lines, in comparison with their parent compounds, acronycine, benzo[a]acronycine, and benzo[b]acronycine.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Tröger's bases in the acronycine, benzo[a]acronycine, and benzo[b]acronycine series](/preview/png/5269359.png "First Page Preview: Tröger's bases in the acronycine, benzo[a]acronycine, and benzo[b]acronycine series")
Authors
Thomas Gaslonde, Stéphane Léonce, Alain Pierré, Bruno Pfeiffer, Sylvie Michel, François Tillequin,