Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269373 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
o-Iodoxybenzoic acid (IBX), a very mild and efficient hypervalent iodine(V) reagent, aromatizes diversely substituted 1-benzylpyrrolidines and N-substituted l-proline analogues to the corresponding substituted pyrroles in good to excellent yields under mild conditions mediated by β-cyclodextrin in water at room temperature. To the best of our knowledge, this is the first report on IBX, promoting complete aromatization leading to N-benzylpyrroles from the corresponding saturated five membered heterocyclic derivatives in water medium.
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Authors
S. Narayana Murthy, Y.V.D. Nageswar,