| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5269429 | Tetrahedron Letters | 2015 | 4 Pages |
Abstract
A convenient one-pot strategy for the regioselective synthesis of cis-β-enaminones has been developed via the condensation of propiolaldehydes and amines in EtOH. This process has opened a new synthetic route to enamines in good yield. A possible reaction mechanism involving a Michael addition/enol tautomerization via a six-membered ring transition state is proposed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wenjuan Shi, Shaofa Sun, Minghu Wu, Bryant Catano, Wan Li, Jian Wang, Haibing Guo, Yalan Xing,