| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5269462 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Two novel diterpenoids, luanchunins A (1) and B (2), along with their precursor, kamebakaurin (3), had been isolated from the stems and leaves of Isodon rubescens var. lushanensis. Their structures were elucidated on the basis of extensive spectroscopic analyses. Compounds 1 and 2 showed potent cytotoxic activity against HL-60 with IC50 values of 4.81 μM and 3.52 μM, respectively. Plausible pathways for the biosynthesis of 1 and 2 were also postulated.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hai-Bo Zhang, Xue Du, Jian-Xin Pu, Yuan-Yuan Wang, Fei He, Yong Zhao, Xiao-Nian Li, Xiao Luo, Wei-Lie Xiao, Yan Li, Han-Dong Sun,