Article ID Journal Published Year Pages File Type
5269486 Tetrahedron Letters 2014 6 Pages PDF
Abstract
The one-pot reactions of aryl glyoxals with acetylacetone and urea using molybdate sulfuric acid (5 mol %) lead to the novel functionalized 5-acetyl-4-(aryloyl)-3,4-dihydropyrimidinones, which readily undergo the Knorr condensation with hydrazines to produce new pyrimido[4,5-d]pyridazines. The present strategies are in accordance with green chemistry principles through the use of a safe and recyclable catalyst under solvent-free conditions.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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