Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269538 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Enantioselective organocatalytic direct aldol reaction of unactivated ketones with various isatin derivatives was developed using cinchonine based urea ligand employing a noncovalent catalysis mechanism. Using this protocol we can access functionalized 3-alkyl-3-hydroxyindolin-2-ones in high yields with good to excellent enantioselectivities.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Suresh Allu, Nagaraju Molleti, Ramachandrarao Panem, Vinod K. Singh,