Article ID Journal Published Year Pages File Type
5269538 Tetrahedron Letters 2011 4 Pages PDF
Abstract

Enantioselective organocatalytic direct aldol reaction of unactivated ketones with various isatin derivatives was developed using cinchonine based urea ligand employing a noncovalent catalysis mechanism. Using this protocol we can access functionalized 3-alkyl-3-hydroxyindolin-2-ones in high yields with good to excellent enantioselectivities.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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