Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269568 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A general method for the Hiyama coupling reaction between aryl halides and 2-trimethylsilylpyridine has been developed. These conditions have been successfully applied to the synthesis of bis-heteroaryl systems, a key disconnection for the pharmaceutical industry in the synthesis of drug-like molecules.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David C. Blakemore, Louise A. Marples,