Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269660 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
Lagunamides, isolated from a marine cyanobacterium Lyngbya majuscule found in Singapore, showed very potent activities against Plasmodium falciparum and murine leukemia cell line (P388). Herein, a concise synthetic approach toward the total synthesis of a lagunamide B analogue is discussed. Macrolactonization, HWE-olefination, and modified Crimmin's aldol are some of the key reactions featured in this synthesis.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sudip Pal, Tushar Kanti Chakraborty,