Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269720 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
Escherichia coli BioH, which is obligatory for biotin synthesis, was found to be an organic solvent tolerant esterase with high enantioselectivity for the kinetic resolution of sec-alcohols using free enzyme powder. With this esterase, a variety of racemic sec-alcohols were efficiently resolved with ee values of up to 99%.
Graphical abstractAn organic solvent tolerant esterase was found exhibiting high enantioselectivity for kinetic resolution of sec-alcohols and a variety of sec-alcohols were efficiently resolved with ee values of up to 99%.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bo Wang, Xiaoling Tang, Ji Liu, Hongwei Yu,