Article ID Journal Published Year Pages File Type
5269720 Tetrahedron Letters 2010 5 Pages PDF
Abstract

Escherichia coli BioH, which is obligatory for biotin synthesis, was found to be an organic solvent tolerant esterase with high enantioselectivity for the kinetic resolution of sec-alcohols using free enzyme powder. With this esterase, a variety of racemic sec-alcohols were efficiently resolved with ee values of up to 99%.

Graphical abstractAn organic solvent tolerant esterase was found exhibiting high enantioselectivity for kinetic resolution of sec-alcohols and a variety of sec-alcohols were efficiently resolved with ee values of up to 99%.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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