| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5269752 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A simple combination of Cu2O and PhCO2H 'on H2O' has been developed as a highly practical and efficient catalytic system for copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). It not only provides a further evidence for the strategy of carboxylic acids-promoted CuAAC, but also offers significant advantages to CuAAC because Cu2O is one of the most stable and cheapest Cu(I) sources; PhCO2H is one of the structurally simplest bidentate ligands; and water is the most 'green' solvent.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Changwei Shao, Rui Zhu, Sheng Luo, Qun Zhang, Xinyan Wang, Yuefei Hu,