| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5269781 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
'Lateritin' (1), a morpholine-2,5-dione (depsipeptide), was reinvestigated for its structure and absolute configuration. On the basis of thorough 1D and 2D NMR and mass spectrometrical analyses, the structure of 1 was revised to be identical with beauvericin (8) and confirmed that beauvericin (8) is the trimeric lactone of 'lateritin' (1). The absolute configuration was determined by acidic hydrolysis, followed by application of Marfey's method, menthyl ester derivatization, and GC-MS analysis. In addition, the specific optical rotation values of the hydrolysis products were compared with those of available standards.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Antonius R.B. Ola, Amal H. Aly, Wenhan Lin, Victor Wray, Abdessamad Debbab,