Article ID Journal Published Year Pages File Type
5269872 Tetrahedron Letters 2014 4 Pages PDF
Abstract

A highly enantioselective domino reaction of α,β-unsaturated aldehydes and 4-acetyl-5-oxohexanal catalyzed by a chiral secondary amine catalyst has been developed, providing an efficient synthetic approach for the synthesis of densely functionalized chiral cyclohexene derivatives with high yields (up to 96%) and enantioselectivities (up to 97% ee) under mild conditions.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry