Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269872 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
A highly enantioselective domino reaction of α,β-unsaturated aldehydes and 4-acetyl-5-oxohexanal catalyzed by a chiral secondary amine catalyst has been developed, providing an efficient synthetic approach for the synthesis of densely functionalized chiral cyclohexene derivatives with high yields (up to 96%) and enantioselectivities (up to 97% ee) under mild conditions.
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