Article ID Journal Published Year Pages File Type
5269900 Tetrahedron Letters 2010 4 Pages PDF
Abstract
The total synthesis of lactonamycin has been achieved. The synthesis includes sequential intramolecular conjugate addition of alcohols to the acetylenic ester, stereoselective glycosylation of the tertiary alcohol, and Michael-Dieckmann type cyclization with the thioester, by which the highly convergent route has been established.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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