Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269935 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A solvent-free synthesis of amides via the coupling of phosphazenes with carboxylic acids is reported. Increasing the rate of heating either by microwave irradiation or conventional heating results in multifold increase in the rate of amide bond formation. Synthesis of a library of amides including a potent antitumour candidate has been accomplished.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Murugan Sathishkumar, Poovan Shanmugavelan, Sangaraiah Nagarajan, Murugesan Maheswari, Murugan Dinesh, Alagusundaram Ponnuswamy,