Article ID Journal Published Year Pages File Type
5269935 Tetrahedron Letters 2011 4 Pages PDF
Abstract
A solvent-free synthesis of amides via the coupling of phosphazenes with carboxylic acids is reported. Increasing the rate of heating either by microwave irradiation or conventional heating results in multifold increase in the rate of amide bond formation. Synthesis of a library of amides including a potent antitumour candidate has been accomplished.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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