Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5269942 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
A highly efficient diastereoselective one-pot synthesis of functionalized piperidines has been developed based on an aqua-compatible ZrOCl2·8H2O catalyst via tandem reactions of aromatic aldehydes, amines, and acetoacetic esters.
Graphical abstractZrOCl2·8H2O catalyzed highly diastereoselective efficient one-pot synthesis of functionalized piperidines from reactions of aromatic aldehydes, amines, and acetoacetic esters has been described.Figure optionsDownload full-size imageDownload as PowerPoint slide
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