Article ID Journal Published Year Pages File Type
5269942 Tetrahedron Letters 2011 5 Pages PDF
Abstract

A highly efficient diastereoselective one-pot synthesis of functionalized piperidines has been developed based on an aqua-compatible ZrOCl2·8H2O catalyst via tandem reactions of aromatic aldehydes, amines, and acetoacetic esters.

Graphical abstractZrOCl2·8H2O catalyzed highly diastereoselective efficient one-pot synthesis of functionalized piperidines from reactions of aromatic aldehydes, amines, and acetoacetic esters has been described.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry