Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270055 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
The selective synthesis of N-(hetero)aryl-1-aminoindoles 3 from the corresponding N-aminoindoles and (hetero)aryl halides using a catalyst combination of Pd2(dba)3 associated to Josiphos is described. By switching to Xantphos as the ligand, the alternate catalytic system allows the coupling to proceed efficiently for the preparation of symmetrical and unsymmetrical N,Nâ²-diaryl-1-aminoindole derivatives in good yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Samir Messaoudi, Jean-Daniel Brion, Mouâd Alami,