| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270072 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
A ruthenium catalyst formed in situ by combining [Ru(p-cymene)Cl2]2 and an amino acid hydroxy-amide was found to catalyze efficiently the asymmetric reduction of aryl alkyl ketones under transfer hydrogenation conditions using ethanol as the hydrogen donor. The secondary alcohol products were obtained in moderate to good yields and with good to excellent enantioselectivity (up to 97% ee).
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Helena Lundberg, Hans Adolfsson,