Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270108 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
α,α-Dibromo-2-methoxyacetophenone reacts, under mild reaction conditions, with C-, N- and O-nucleophiles via a bromophilic substitution/protonation/carbophilic substitution cascade process to afford α-monosubstituted-2-methoxyacetophenones in moderate to good yield. The only exception from this reaction pathway is the reaction with the anion derived from malononitrile in which 2-aroyl-1,1,3,3-tetracyanopropene is obtained.
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Chemistry
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Authors
Jovana Tatar, Rade MarkoviÄ, Milovan StojanoviÄ, Marija Baranac-StojanoviÄ,