| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270113 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A series of secondary amine-thiourea catalysts derived from l-proline and chiral diamine were prepared and successfully applied to the highly effective and enantioselective α-amination of unmodified aldehydes with various azodicarboxylates in excellent yields (up to 99%) and enantioselectivities (up to 99% ee) within a few minutes.
Graphical abstractA series of secondary amine-thiourea catalysts derived from l-proline and chiral diamine were prepared and first applied to highly enantioselective amination of unmodified aldehydes with various azodicarboxylates in excellent yields (up to 99%) and enantioselectivities (up to 99% ee) within a few minutes.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ji-Ya Fu, Qing-Chun Huang, Qiao-Wei Wang, Li-Xin Wang, Xiao-Ying Xu,