Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270174 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
Magnetically separable Fe3O4 nanoparticles endow with an efficient and economic route for the synthesis of propargylamines by the three-component coupling of aldehyde, amine, and alkyne through C-H activation. The reaction is especially effective for reactions involving aliphatic aldehydes and no additional co-catalyst or activator is required. High catalytic activity and ease of recovery using an external magnetic field are additional eco-friendly attributes of this catalytic system. The catalyst was recycled for five times without a significant loss of catalytic activity.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
B. Sreedhar, A. Suresh Kumar, P. Surendra Reddy,