Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270198 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
A mild and efficient tandem process for the synthesis of new highly substituted 2-pyrones starting from commercially available 2-arylacetic acids has been developed. The synthesis is based on the Knoevenagel condensation of 1,3-cyclohexadiones with various β-formyl-esters, followed by lactonization in the presence of nano ZnO (20 mol %). Moderate to high yields and readily available cheap starting materials are the key features of the present method.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Firouz Matloubi Moghaddam, Zohreh Mirjafary, Marjan Jebeli Javan, Sara Motamen, Hamid Saeidian,