| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270217 | Tetrahedron Letters | 2014 | 5 Pages |
Abstract
An efficient synthesis of unsymmetrically substituted 1,3-pyrazole derivatives has been developed via three-component coupling reaction involving 3-(dimethylamino)-1-phenylprop-2-en-1-one, hydrazine, and aryl halides in one pot process exhibiting high regioselectivity. The pyrazole synthesis proceeds via a sequential series of reactions such as Michael addition, heterocyclization, dehydration, and Ullmann cross-coupling.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Akula Raghunadh, Suresh Babu Meruva, Ramamohan Mekala, K. Raghavendra Rao, Thalishetti Krishna, R. Gangadhara Chary, L. Vaikunta Rao, U.K. Syam Kumar,