| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270251 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
In this Letter, we wish to disclose a new strategy for the construction of substituted γ-butyrolactones. The latter might not only be of potential interest in terms of biological activity and synthesis but also allow access to original heterocyclic scaffolds. According to previous study, efficient two-step sequence involving Eschenmoser-Claisen rearrangement and acid-lactonization reaction was successfully applied for the construction of original fused bicyclic γ-butyrolactones based on an 1,4-oxazine core.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Access to novel bicyclic fused γ-butyrolactone using [3,3]-sigmatropic rearrangement and acid-lactonization sequence as key transformation](/preview/png/5270251.png "First Page Preview: Access to novel bicyclic fused γ-butyrolactone using [3,3]-sigmatropic rearrangement and acid-lactonization sequence as key transformation")
Authors
Elise Claveau, Erwan Noirjean, Pascal Bouyssou, Gérard Coudert, Isabelle Gillaizeau,