| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270258 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
An easy and straightforward synthesis of spiroindenyl heterocycles by the repeated treatment of boron trifluoride etherate (BF3-OEt2) is reported. The overall transformation from ketones 1 to spiro-fused indenes 3 proceeds via Wittig olefination, deconjugation, Grignard addition, and intramolecular electrophilic cyclization in moderate yields. It presents a novel rearrangement reaction catalyzed by boron trifluoride etherate and broadens the scope of application.
Related Topics
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Authors
Meng-Yang Chang, Chung-Han Lin, Yeh-Long Chen, Ru-Ting Hsu, Ching-Yao Chang,