Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5270292 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
A rhodium-catalyzed oxidative C2-alkenylation of indoles containing a N-(p-tolyl)carboxamide group with substituted alkynes via CC bond formation and subsequent CN bond cleavage has been described. This protocol represents direct access to C2-alkenylated free (NH)-indoles, which are important building blocks in the synthesis of natural and pharmacological compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Satyasheel Sharma, Sangil Han, Youngmi Shin, Neeraj Kumar Mishra, Hyunji Oh, Jihye Park, Jong Hwan Kwak, Beom Soo Shin, Young Hoon Jung, In Su Kim,