| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270323 | Tetrahedron Letters | 2017 | 5 Pages |
Abstract
ATH reductions of aliphatic ketones in water catalyzed by ruthenium coordinated by prolinamide ligands produce alcohols with moderate enantiomeric excesses in most cases. A set of seven aliphatic ketones is proposed for a rapid evaluation of the enantioselectivity of catalysts by one-pot multi-substrates reduction. The screening of a library of prolinamides shows that according to the structure of the ketones different ligands give the best asymmetric inductions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mourad Boukachabia, Saoussen Zeror, Jacqueline Collin, Jean-Claude Fiaud, Louisa Aribi Zouioueche,