| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5270365 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A selective and practical approach for the formation of cis-1,4-aminocyclohexanol was developed. The key transformation involves a one-pot imine formation/ Lewis acid-directed imine reduction and results in a highly selective attack of the reducing agent. This simple and practical method is easily amenable to large-scale synthesis.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Fabrice Gallou, Bo Han, Jiang Lu, Manuela Seeger-Weibel, Anne-Florence Stoessel, Simon Allmendinger,